F. Huseynov, E. Mukhtarli. Main Medical Department MOJ, Baku, Azerbaijan.
Aim: Analysis of risk factors influencing to reason-out "failure" and "death" among DR-ТВ patients on treatment with 2nd line anti-ТВ drugs.
Methods: Medical records of first 150 DR-ТВ patients enrolled in treatment with 2nd line anti-TB drugs in penitentiary sector of Azerbaijan have been analyzed in accordance to WHO Guidelines on DR-TB management. 21 of this patients were ex-prisoners followed-up in civilian sector after release from prison in frame of Tripartite Agreement signed between Main Medical Department of the Ministry of Justice, Ministry of Health and International Committee of the Red Cross.
Results: Since April 2007 to May 2009, 150 DR- TB patients were enrolled to treatment with 2nd line anti-TB drugs. Treatment results of them are as stated below: "cured" 108 (72%), "death" 12 (8%), "failure" 15 (10%), "default" 15 (10%). Patients with "dead" and "failure" reason-out had broader resistance rate, two-sided destruction (cavernous) ТВ and majority of them had co-infection with Hepatitis С during integration to treatment.
Conclusion: Resistance rate, spread level of tuberculosis process and concomitant pathologies are risk factors significantly influencing to treatment results. It is necessary to continue surveillances for evaluation of their role more precisely.